A recent publication by Ozge Sensoy Bahar, Co-Director of the International Center for Child Health and Development (ICHAD), in the journal Lancet Child & Adolescent Health addresses the pressing issue of adolescent girls’ vulnerability to child labor and migration in Ghana. The paper is a call to action for national and local leaders, policymakers, researchers, and community stakeholders to collaborate on developing and implementing evidence-based and theory-informed programs to protect and support vulnerable and adolescent girls.